Prognostic importance of thrombospondin-1, VEGF, PDGFR- β in diffuse large B-cell lymphoma

Aim: In this study, we aimed to investigate the relationship between staining rates of thrombospondin-1, VEGF, and PDGFR-in tissue preparations in patients diagnosed with DLBCL their clinical features at time diagnosis, response treatment prognosis.
 Material Method: A total 44 a diagnosis 13 control reactive lymphadenopathy were included study. After immunohistochemical pathology patient groups PDGFR-β thrombospondin-1 stains, characteristics survival analysis statistically analyzed.
 Results: When compared group terms PDGFR-β, rates, found that was lower (p=0.009). Although it not significant for observed 5-year OS PFS values low high levels expression, on contrary, thrombospondin rate. negative correlation (p=0.003, r=-0.440). 
 Conclusion: As result, although no VEGF our effective prognosis. PDGFR-β.